Vesicular and Bullous type skin diseases
Diagnosis
Erythema
multiforme is not as
a
rule difficult to diagnose,
but the vesicular and bullous type
may have to be distinguished
from pemphigoid. Erythema multiforme
occurs in a much
younger age group and is
a more obviously centrifugal disease,
affecting the hands and
feet,
elbows, knees and neck. Cases with
small vesicles may cause
confusion with dermatitis herpetiformis.
In the latter disease the
eruption tends to be
less
symmetrical, has less
tendency to be limited
to the extremities, irritates
much more, and is often
accompanied by an eosinophilia. Cases
with the eruption chiefly on
the face may be
confused
with lupus erythematosus .
In this disease, however,
the nose and ears are often
affected and the follicles
on the affected part are
filled with little horny
plugs which give the skin a
stippled appearance. Lupus
erythematosus usually follows a,
very chronie course while
erythema multiforme is essentially
an acute disease.
Prognosis. The
eruption will probably disappear
in two to three
weeks leaving no scars,
but it is very
liable to recur.
Treatment
Every effort should
be made by means
of a careful history
and
thorough general examination to
find a cause and
this should then be
treated. Little else can
be done and no drug has
any specific effect in
the condition. When
the mucous membranes are involved,
especially
those in the eye,
local or systemic antibiotics may
be
needed to control
secondary infection. Steroid hormones
given systematically appear
to be helpful in
certain of the severe bullous
and mucosal cases.
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